Professor Kayama could have been happy with his job, except that all of the students on campus hate him, and he hates them back. Miki Watase is a dark-haired vixen who will do anything to raise her grades, but when Professor Kayama refuses play along, she's determined to have revenge. She gathers her friends - the luscious Hinata, the slutty Arisa, and the beautiful but timid Sachie - and they mix drug-laced alcohol with a snap-shot camera to publicly humiliate Kayama.

However, these vivacious little co-eds are about to discover that even a wimpy professor like Kayama has his limits. Now he's going to teach them a real lesson in humility that will have them each begging for forgiveness.